Cyproheptadine Hydrochloride

In the US, prescription cyproheptadine is indicated for the treatment of various allergic symptomatologies – including dermatographia, rhinitis, conjunctivitis, and urticaria – as well as adjunctive therapy in the management of anaphylaxis following treatment with epinephrine. In Canada, cyproheptadine is available over-the-counter and is indicated for the treatment of pruritus and for appetite stimulation. In Australia, cyproheptadine is additionally indicated for the treatment vascular headaches.

Cyproheptadine is also used off-label for the treatment of serotonin syndrome.

Chemical Name: Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride, sesquihydrate.
4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine hydrochloride sesquihydrate.

BP2020 & USP43